Graph convolutional neural networks have shown significant potential in natural and histopathology images. However, their use has only been studied in a single magnification or multi-magnification with late fusion. In order to leverage the multi-magnification information and early fusion with graph convolutional networks, we handle different embedding spaces at each magnification by introducing the Multi-Scale Relational Graph Convolutional Network (MS-RGCN) as a multiple instance learning method. We model histopathology image patches and their relation with neighboring patches and patches at other scales (i.e., magnifications) as a graph. To pass the information between different magnification embedding spaces, we define separate message-passing neural networks based on the node and edge type. We experiment on prostate cancer histopathology images to predict the grade groups based on the extracted features from patches. We also compare our MS-RGCN with multiple state-of-the-art methods with evaluations on both source and held-out datasets. Our method outperforms the state-of-the-art on both datasets and especially on the classification of grade groups 2 and 3, which are significant for clinical decisions for patient management. Through an ablation study, we test and show the value of the pertinent design features of the MS-RGCN.

Deep learning, especially convolutional neural networks, has triggered accelerated advancements in computer vision, bringing changes into our daily practice. Furthermore, the standardized deep learning modules (also known as backbone networks), i.e., ResNet and EfficientNet, have enabled efficient and rapid development of new computer vision solutions. Yet, deep learning methods still suffer from several drawbacks. One of the most concerning problems is the high memory and computational cost, such that dedicated computing units, typically GPUs, have to be used for training and development. Therefore, in this paper, we propose a quantifiable evaluation method, the convolutional kernel redundancy measure, which is based on perceived image differences, for guiding the network structure simplification. When applying our method to the chest X-ray image classification problem with ResNet, our method can maintain the performance of the network and reduce the number of parameters from over $23$ million to approximately $128$ thousand (reducing $99.46\%$ of the parameters).

Purpose: Trans-oral robotic surgery (TORS) using the da Vinci surgical robot is a new minimally-invasive surgery method to treat oropharyngeal tumors, but it is a challenging operation. Augmented reality (AR) based on intra-operative ultrasound (US) has the potential to enhance the visualization of the anatomy and cancerous tumors to provide additional tools for decision-making in surgery. Methods: We propose and carry out preliminary evaluations of a US-guided AR system for TORS, with the transducer placed on the neck for a transcervical view. Firstly, we perform a novel MRI-transcervical 3D US registration study. Secondly, we develop a US-robot calibration method with an optical tracker and an AR system to display the anatomy mesh model in the real-time endoscope images inside the surgeon console. Results: Our AR system reaches a mean projection error of 26.81 and 27.85 pixels for the projection from the US to stereo cameras in a water bath experiment. The average target registration error for MRI to 3D US is 8.90 mm for the 3D US transducer and 5.85 mm for freehand 3D US, and the average distance between the vessel centerlines is 2.32 mm. Conclusion: We demonstrate the first proof-of-concept transcervical US-guided AR system for TORS and the feasibility of trans-cervical 3D US-MRI registration. Our results show that trans-cervical 3D US is a promising technique for TORS image guidance.

我们提出了一个基于变压器的NERF（Transnerf），以学习在新视图合成任务的观察视图图像上进行的通用神经辐射场。相比之下，现有的基于MLP的NERF无法直接接收具有任意号码的观察视图，并且需要基于辅助池的操作来融合源视图信息，从而导致源视图与目标渲染视图之间缺少复杂的关系。此外，当前方法分别处理每个3D点，忽略辐射场场景表示的局部一致性。这些局限性可能会在挑战现实世界应用中降低其性能，在这些应用程序中可能存在巨大的差异和新颖的渲染视图之间的巨大差异。为了应对这些挑战，我们的Transnerf利用注意机制自然地将任意数量的源视图的深层关联解码为基于坐标的场景表示。在统一变压器网络中，在射线铸造空间和周围视图空间中考虑了形状和外观的局部一致性。实验表明，与基于图像的最先进的基于图像的神经渲染方法相比，我们在各种场景上接受过培训的Transnf可以在场景 - 敏捷和每个场景的燃烧场景中获得更好的性能。源视图与渲染视图之间的差距很大。